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Old 11-06-2008, 11:58 PM   #1
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Oral sex blamed for throat cancer rise

June 10, 2008 - 2:57PM

For five gruelling months in 2006 and 2007, Carol Kanga suffered through treatment for a life-threatening case of throat cancer linked to an unlikely source: a sexually transmitted viral infection.

Unable to swallow food or water during chemotherapy and radiation treatment, Kanga was fed through a stomach tube. Her one respite came on Thanksgiving, when she savoured a single spoonful of weak broth.

"The radiation basically burns the skin off the outside and inside of your throat," said Kanga, 52. "It's like there's a fire inside your neck."

Kanga's treatment was successful, but the virus that struck her is causing increasing concern among some researchers who think it is causing a small-scale epidemic of throat cancer.

That virus, scientists have proved only in the last two years, is human papillomavirus, or HPV - the same virus that's behind most cases of cervical cancer.

With 6,000 cases per year and an annual increase of up to 10 per cent in men younger than 60, some researchers say the HPV-linked throat cancers could overtake cervical cancer in the next decade.

"It's almost a new disease, in a sense," said Dr Ezra Cohen, an oncologist at the University of Chicago Medical Centre. "It's now becoming a dominant sub-type of the disease that we see in our clinic."

The HPV infections likely took root decades ago as the Baby Boomers were reaching adulthood, and only now are spurring a rise in throat cancer cases, mostly among men and women in their 50s.

No one understands the precise reason for the increase, though experts suspect it's linked to changes in sexual practices that emerged in the 1960s and '70s. For example, oral sex is a known risk factor for HPV-related throat cancers, and studies have shown that people who have come of age since the 1950s are more likely to have engaged in oral sex than those who were born earlier.

"Those people were in their teens during the sexual revolution, so they may be leading the wave," said Dr Maura Gillison, a professor of oncology and epidemiology at the Johns Hopkins Kimmel Cancer Centre who has published numerous studies indicating that HPV-related throat cancer is a distinct type of disease.

The virus targets a specific portion of the upper throat called the oropharynx, which includes the tonsils and base of the tongue. Just a decade ago, doctors believed nearly all such cancers were linked with smoking or extremely heavy drinking.

Last year, however, Gillison's team published a major study that found stark differences between the risky behaviours of throat cancer patients with HPV and those without. The HPV-positive cancer patients tended to have had higher numbers of sex partners than the others and were far more likely to have had multiple oral-sex partners.

The virus-linked cancer appears somewhat less deadly than throat cancers that arise from smoking or drinking. A paper published this year found that 96 per cent of HPV-positive patients survived at least two years after diagnosis, compared with 62 per cent survival for HPV-negative cancers.

"They have a better prognosis, but these are still very aggressive cancers," said Dr Marshall Posner, medical director of head and neck oncology at the Dana-Farber/Harvard Cancer Centre in Boston.

While doctors had hoped for an overall drop in throat cancer as the percentage of Americans who smoke declined, the rise of HPV-related throat cancers seems to be offsetting any such benefit.

Gillison's group tested hundreds of head and neck tumours that doctors began saving in the early 1970s, long before anyone knew such cancers might be linked to HPV. The work showed that the number of HPV-positive tumours increased by about 1 per cent a year on average, though the trend has quickened in the last decade, especially in men younger than 60.

The virus thrives in the outer layer of skin and is transmitted mostly by skin-to-skin contact, researchers think. Sexual transmission tends to cause infection near the site of contact; intercourse is linked with cervical cancer, while oral sex can cause cancer of the upper throat.

Recent increases in HPV-positive throat cancers could be an aftershock of changes in sexual behaviour that began decades ago. A landmark 1994 study of sexual behaviour showed that oral sex had become commonplace only in the generations born in the 1950s or later. Fewer than 60 per cent of people born in the 1930s were found to have had oral sex, compared with more than 80 per cent of people born since 1950.

"The older people simply did not do it as much," said Edward Laumann, a University of Chicago professor of sociology who led the National Health and Social Life Survey.

"It's a very complicated social story that nobody's really worked out in detail," he said.

Other causes may have contributed to the spread of HPV cancers, including the increased movement of people around the country and the world in the last half-century, experts said. Scientists aren't even sure yet whether the virus might be spread by kissing, though data suggest oral sex is a major route of transmission.

One implication of the cancer trend is that oral sex does not constitute "safe sex," Kanga said.

"We can't be afraid to talk about this," Kanga said. "The message that oral sex carries risks is just not out there."

Conservative groups say the emergence of HPV-related throat cancer is an additional argument for abstaining from sex until marriage.

But many researchers focus on expanded use of the HPV vaccine, which since 2006 has been recommended for girls ages 11 to 12. Just as the vaccine lessens the risk of cervical cancer for those girls, it may offer protection from HPV-positive throat cancer, though studies have not yet addressed that question.

Vaccine maker Merck & Co hopes to submit an application this year to the US Food and Drug Administration for use of its HPV vaccine in males. Although the company's studies will not show specifically whether the vaccine protects against throat cancer, they should reveal whether the shots prevent infection with HPV.

"We expect the vaccine to work just as well in male and female populations," said Dr Richard Haupt, director of Merck's clinical program for the vaccine, Gardasil, which was developed using technology pioneered in Australia.

MCT
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Old 12-06-2008, 03:28 AM   #2
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We need a program called Guardagardasil, a guard against Gardasil, to protect us from the destruction of our immune systems and the destruction of our cells, including brain cells which is the reason why people who are vaccinated quickly get Alzheimers. The use of vaccines is also the main reason why children are becoming more autistic. And it's also a major cause for the increase of cancer in all age groups.
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Old 12-06-2008, 03:51 AM   #3
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The medical profession is the leading cause of death and that includes big pharma and vaccines. Only go to a doctor in cases of extreme emergency. The same with the use of medicine. Only use medicine if nothing else will save your life. For the common person, there should be no need whatsoever to ever go to a doctor or a dentist.
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Old 12-06-2008, 04:34 AM   #4
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The health industry feeds on us being sick. This is true for both private and public health care. It's a vampiric system. We have been so thoroughly programmed and indoctrinated to believe the health care system is something good that we have become dependent on it. The truth is that the health care system is a piece of shit. Wake up you fools!
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Old 12-06-2008, 09:04 AM   #5
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Western medicine treats disease at the enemy and creates other disease in the process. I have vowed never to undergo chemo or radiation treatment. If this ever happened to me, I would firstly think about what's up psychologically and look to alternative methods. I believe in the Vit B-17 information that I've seen posted on this site.
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Old 12-06-2008, 09:21 AM   #6
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Quote:
Originally Posted by icke_is_right View Post
Western medicine treats disease at the enemy and creates other disease in the process. I have vowed never to undergo chemo or radiation treatment. If this ever happened to me, I would firstly think about what's up psychologically and look to alternative methods. I believe in the Vit B-17 information that I've seen posted on this site.
Someone said that western medicine is good at trauma procedures, such as surgery, and that eastern medicine such as Ayurveda etc is better for fixing ordinary diseases. Western medicine seldom fixes the problem it seems and people have to take big pharma drugs year after year with loads of side effects.

My latest idea is to try to turn my belief system upside down when it comes to health care. The ordinary belief is that health care is something good and needed. My new belief is that health care is baaaaad. My idea is that our beliefs perhaps act as magnets for things, and with the belief that health care is needed, that belief will make it come true by making the body sick!

The idea of changing belief can be totally crazy, but if it turns out to be a bad idea I can always go back to believing health care is needed again.
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Old 12-06-2008, 03:04 PM   #7
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Originally Posted by Anders Lindman View Post
Someone said that western medicine is good at trauma procedures, such as surgery, and that eastern medicine such as Ayurveda etc is better for fixing ordinary diseases. Western medicine seldom fixes the problem it seems and people have to take big pharma drugs year after year with loads of side effects.

My latest idea is to try to turn my belief system upside down when it comes to health care. The ordinary belief is that health care is something good and needed. My new belief is that health care is baaaaad. My idea is that our beliefs perhaps act as magnets for things, and with the belief that health care is needed, that belief will make it come true by making the body sick!

The idea of changing belief can be totally crazy, but if it turns out to be a bad idea I can always go back to believing health care is needed again.
When you have very bad experiences with western medicine, (as I have), then you experience something like Applied Kinesiology, it blows you away. I am considering studying this at the moment. I find it amazing.
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