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This topic is for all general discussion regarding the current COVID-19 pandemic. There are of course numerous other related topics for discussing specific aspects of this pandemic in more detail. And there are other parts of this forum for more 'off-topic' discussions.

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Apologies if this has already been discussed previously, but would anyone have a link to the ingredients of the CureVac vaccine?

 

Whilst not taking bullshit vaccines for a fake disease myself, I do know a local representative in NI who says he wouldn't touch any vaccine with or made from aborted human fetal material. He has been "informed" that the CureVac vaccine has been made without the aforementioned.

 

Whilst I personally would think the mRNA element should scare of any true pro-lifer (as opposed to a "fetal rights only Pro-Lifer"), I'd love to furnish him with any available information as I recognise through communicating with him that, while he still believes there is a real virus in spite of all evidence to the contrary, he would not on "ethical" grounds take anything with a link to abortion/aborted fetuses. This is religious NI remeber ;-)

 

He is fairly influential in his community and a few less vaccinated people for whatever reason is worth the effort. Perhaps. Not entirely convinced. But still.

 

 

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6 hours ago, Avoiceinthecrowd said:

As far as I know vaccine companies patent their formula. Meaning each manufacturer will have elements that are different from each other either in quantity or chemical type.

Yip. They maybe able to rattle off some ingredients, such as the lipid nanoparticles (polyethylene glycol (PEG) a known allergen) that surround the compound and other bits and pops, but the chemistry of the synthetic mRNA is patented.

 

What, exactly, the Covid vaccine is made of is a question of chemistry in the creation of that synthetic mRNA, which Dr Weissman said is propriety information and would be buried in a complex web of patents.  

Neither Pfizer nor Moderna immediately responded to requests for a breakdown of the chemistry in BNT162b2 or mRNA-1273.

 

What is Covid vaccine made of? Scientist behind Pfizer and Moderna vaccine technology explain

https://www.independent.co.uk/news/world/americas/covid-19-pfizer-vaccine-ingredients-b1774537.html

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7 minutes ago, AdvaitaV said:

Apologies if this has already been discussed previously, but would anyone have a link to the ingredients of the CureVac vaccine?

 

Whilst not taking bullshit vaccines for a fake disease myself, I do know a local representative in NI who says he wouldn't touch any vaccine with or made from aborted human fetal material. He has been "informed" that the CureVac vaccine has been made without the aforementioned.

 

Whilst I personally would think the mRNA element should scare of any true pro-lifer (as opposed to a "fetal rights only Pro-Lifer"), I'd love to furnish him with any available information as I recognise through communicating with him that, while he still believes there is a real virus in spite of all evidence to the contrary, he would not on "ethical" grounds take anything with a link to abortion/aborted fetuses. This is religious NI remeber ;-)

 

He is fairly influential in his community and a few less vaccinated people for whatever reason is worth the effort. Perhaps. Not entirely convinced. But still.

 

 

It doesn't have to contain fetus cells... Probably it won't - they use fetus to grow viruses on it. Maybe they used rats instead.

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This journalistic piece has been published in the BMJ about the hacked Pfizer / EMA documents - @metak88 posted the link to the hacked documents some weeks back.

 

What the hacked documents have revealed is that Pfizer were having batch integrity issues as the mRNA in use was not stable and subject to breaking down into two differing fragments which may be one reason why the product has to be stored at such a low temperatures and must be used within a short time of defrosting. No safety studies have been conducted on mRNA integrity.


https://www.bmj.com/content/372/bmj.n627?fbclid=IwAR2WrxDS5Vf9WtyoXauQFofXTsTKdEAlj-X6Ko-iS6wyKE1TSfvmceYVtxY

The EMA covid-19 data leak, and what it tells us about mRNA instability

Leaked documents show that some early commercial batches of Pfizer-BioNTech’s covid-19 vaccine had lower than expected levels of intact mRNA, prompting wider questions about how to assess this novel vaccine platform, writes Serena Tinari

 

Quote

As it conducted its analysis of the Pfizer-BioNTech covid-19 vaccine in December, the European Medicines Agency (EMA) was the victim of a cyberattack.1 More than 40 megabytes of classified information from the agency’s review were published on the dark web, and several journalists—including from The BMJ—and academics worldwide were sent copies of the leaks. They came from anonymous email accounts and most efforts to interact with the senders were unsuccessful. None of the senders revealed their identity, and the EMA says it is pursuing a criminal investigation.

The BMJ has reviewed the documents, which show that regulators had major concerns over unexpectedly low quantities of intact mRNA in batches of the vaccine developed for commercial production.

 

EMA scientists tasked with ensuring manufacturing quality—the chemistry, manufacturing, and control aspects of Pfizer’s submission to the EMA—worried about “truncated and modified mRNA species present in the finished product.” Among the many files leaked to The BMJ, an email dated 23 November by a high ranking EMA official outlined a raft of issues. In short, commercial manufacturing was not producing vaccines to the specifications expected, and regulators were unsure of the implications. EMA responded by filing two “major objections” with Pfizer, along with a host of other questions it wanted addressed.

 

The email identified “a significant difference in % RNA integrity/truncated species” between the clinical batches and proposed commercial batches—from around 78% to 55%. The root cause was unknown and the impact of this loss of RNA integrity on safety and efficacy of the vaccine was “yet to be defined,” the email said.

 

Ultimately, on 21 December, EMA authorised Pfizer-BioNTech’s vaccine. The agency’s public assessment report, a technical document published on its website, noted, “the quality of this medicinal product, submitted in the emergency context of the current (covid-19) pandemic, is considered to be sufficiently consistent and acceptable.”2

 

It’s unclear how the agency’s concerns were satisfied. According to one of the leaked emails dated 25 November, positive news had come from an undisclosed source in the US: “The latest lots indicate that % intact RNA are back at around 70-75%, which leaves us cautiously optimistic that additional data could address the issue,” the email said.

A near miss?

It’s also unclear whether the events in November constitute a near miss in the commercial manufacturing of mRNA vaccines.

 

EMA says the leaked information was partially doctored, explaining in a statement that “whilst individual emails are authentic, data from different users were selected and aggregated, screenshots from multiple folders and mailboxes have been created, and additional titles were added by the perpetrators.”3

 

But the documents offer the broader medical community a chance to reflect on the complexities of quality assurance for novel mRNA vaccines, which include everything from the quantification and integrity of mRNA and carrier lipids to measuring the distribution of particle sizes and encapsulation efficiency. Of particular concern is RNA instability, one of the most important variables relevant to all mRNA vaccines that has thus far received scant attention in the clinical community. It is an issue relevant not just to Pfizer-BioNTech’s vaccine but also to those produced by Moderna, CureVac, and others,4 as well as a “second generation” mRNA vaccine being pursued by Imperial College London.5

 

RNA instability is one of the biggest hurdles for researchers developing nucleic acid based vaccines. It is the primary reason for the technology’s stringent cold chain requirements and has been addressed by encapsulating the mRNA in lipid nanoparticles (box).

 

“The complete, intact mRNA molecule is essential to its potency as a vaccine,” professor of biopharmaceutics Daan J.A. Crommelin and colleagues wrote in a review article in The Journal of Pharmaceutical Sciences late last year. “Even a minor degradation reaction, anywhere along a mRNA strand, can severely slow or stop proper translation performance of that strand and thus result in the incomplete expression of the target antigen.”6

 

Crommelin and colleagues note that specific regulatory guidance for mRNA based vaccines has yet to be developed, and The BMJ’s attempts to clarify current standards were unsuccessful.

Transparency and confidentiality

The BMJ asked Pfizer, Moderna, and CureVac, as well as several regulators, what percentage mRNA integrity they consider acceptable for vaccines against covid-19. None offered any specifics.

The Medicines and Healthcare products Regulatory Agency, the UK’s medicines regulator, acknowledged the lack of a specified percentage RNA integrity, but declined to provide further detail. “The specification limit acceptance criteria are commercially confidential,” the agency said in an email.

 

The US Food and Drug Administration (FDA) directed The BMJ to read its guidance documents78 and its review of Pfizer’s vaccine,9 but none of these specify the percentage RNA the agency is requiring. Asked to comment, the regulator pointed to Pfizer: “information that you seek that is not addressed in the FDA Review Memorandum should be directed to Pfizer.”

 

In subsequent correspondence, FDA, EMA, and Canadian government department Health Canada all stated that specific information related to the acceptability criteria is confidential.

 

EMA did acknowledge, however, that vaccine efficacy depends on the presence of suitable amounts of intact mRNA. In the case of the commercial batches that first raised alarm bells, the agency told The BMJ that the levels of truncated mRNA “and the amounts of a potential protein produced by the truncated mRNA would be too low to constitute a safety risk.” EMA did not comment on how truncated mRNA might affect efficacy. The issue was satisfactorily addressed, the agency underlined, when further information was supplied by the manufacturer.

 

Health Canada told The BMJ that Pfizer had conducted investigations into the root cause of reduced integrity in the commercial vaccine batches, and “changes were made in their processes to ensure that the integrity was improved and brought in line with what was seen for clinical trial batches.” Health Canada said the three agencies subsequently determined that “there was no concern with the RNA integrity or any other product specifications.”

 

Correspondence in the leaked documents suggests that FDA, Health Canada, and EMA were aligned on clinically qualified specifications of percentage mRNA integrity. Health Canada has confirmed to The BMJ that regulators “have worked together to align those requirements,” but all agencies declined to share with The BMJ any specifics on grounds that such information was commercially sensitive.

 

Pfizer also declined to comment on what percentage mRNA integrity it is aiming for, nor would it address questions about the cause of the unexpectedly low percentage mRNA integrity in certain batches, leaving open the question of whether it could happen again. Pfizer stressed: “Each batch of vaccines is tested by the official medicinal control laboratory—the Paul Ehrlich Institute in Germany—before final product release. As a result, the quality of all vaccine doses that are placed on the market in Europe has been double tested to ensure compliance with the specifications agreed upon with the regulatory authorities.”

 

Moderna’s chief corporate affairs officer Ray Jordan declined to respond to any of The BMJ’s questions, stating: “At this point, Moderna will not be offering additional commentary on these topics.”

 

CureVac, whose mRNA vaccine was submitted for EMA’s “rolling review” in February,10 told The BMJ that “it is too soon to give details.”

 

The shortage of information may reflect the lack of certainty, even among regulators, about how to assess the evidence fully for this novel technology. Professor Crommelin told The BMJ that, “For small, low molecular weight products, the active pharmaceutical ingredient integrity is typically close to 100%.”

 

But for mRNA vaccines? “Experience with mRNA integrity is limited.”

 

 

 

 

 

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9 minutes ago, skitzorat said:

Yip. They maybe able to rattle off some ingredients, such as the lipid nanoparticles (polyethylene glycol (PEG) a known allergen) that surround the compound and other bits and pops, but the chemistry of the synthetic mRNA is patented.

 

What, exactly, the Covid vaccine is made of is a question of chemistry in the creation of that synthetic mRNA, which Dr Weissman said is propriety information and would be buried in a complex web of patents.  

Neither Pfizer nor Moderna immediately responded to requests for a breakdown of the chemistry in BNT162b2 or mRNA-1273.

 

What is Covid vaccine made of? Scientist behind Pfizer and Moderna vaccine technology explain

https://www.independent.co.uk/news/world/americas/covid-19-pfizer-vaccine-ingredients-b1774537.html

Reminds me Hitler's remedy - Bulgarian shoe-salesman faeces... 🤭

plankton.jpg

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On 3/10/2021 at 3:32 AM, FrankVitali said:

in China they scan you face and you get deducted points if your not happy and smiling.

As David says, China Today; the West Tomorrow.

Drone trackers and QR codes are the least of our worries - they're coming for our children!

 

A.I. headbands that shows teachers in real time if a child is paying attention.

 

 

China's Xi Jinping is pushing for a global Covid QR code.

 

"We hope more countries will join this mechanism," Xi said.

 

https://edition.cnn.com/2020/11/23/asia/china-xi-qr-code-coronavirus-intl-hnk/index.html

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1 hour ago, perpetual said:

I've shown believers that same piece of evidence of pre-planning and it didn't register with them at all. 

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Letter sent to Irish Government regarding massive rise in excess nursing home deaths since vacination roll out.


 

Dear Deputy,

We are contacting you as Teachta Dála and a sitting member of Dáil Éireann.

We wish to make you aware of a very serious rise in the number of nursing home deaths (excess deaths) for the three-week period beginning at the end January 2021. The attached chart (page 3) shows 160 deaths from a selection of just 10 of the 572 HIQA registered nursing homes that we studied during the period mentioned. In comparison there were only a small number of deaths in those same nursing homes during December 2020 and January 2021. Considering the overall reduction in COVID-19 related deaths, hospitalisations and positive PCR tests for the same period, the dramatic rise in deaths gives us great cause for concern. Please refer to the attached graph on page 4 showing data for these key trends.

Contd........

https://healthfreedomireland.com/letter-sent-to-government-re-dramatic-rise-in-excess-nursing-home-deaths/

Edited by Roscommon
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9 hours ago, alexa said:

 

Soz, but I have to disagree with you here, Jesus is our only salvation out of this mess we find ourselves in.

 

It's true God did favor the Jews until they crucified Jesus. Hence the reason for Paul's preaching to blend the Jews and the Gentiles together.

 

I respect your beliefs and don't want to cause offence but looking for saviours/messiahs to come and save us is the last thing humanity needs to do in fact it's one of the main reasons we're in this mess.

If you want to believe in Jesus then great but maybe it's time the human race grew up, took responsibility and decided that if they want change in the world then they'll have to do it themselves, get off their knees and stop looking to the sky for help.

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2 hours ago, Lamp Of Truth said:

 

Of course they don't know, the types of people who get the vaccine get all their news and info from the MSM who won't tell them the truth about the so called vaccine.

Do you think the nurses and doctors administering the vaccine have any idea what's in it ?? I very much doubt it.

 

I wonder how many of them know that taking part in a medical trial voids their life insurance and some private pension payouts after death?????!!!!!!        

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6 minutes ago, Lamp Of Truth said:

 

I respect your beliefs and don't want to cause offence but looking for saviours/messiahs to come and save us is the last thing humanity needs to do in fact it's one of the main reasons we're in this mess.

If you want to believe in Jesus then great but maybe it's time the human race grew up, took responsibility and decided that if they want change in the world then they'll have to do it themselves, get off their knees and stop looking to the sky for help.

 

Your not causing me any offence, only God, which in these precarious times that we find ourselves living in, isn't the wisest of moves.

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1 minute ago, alexa said:

 

Your not causing me any offence, only God, which in these precarious times that we find ourselves living in, isn't the wisest of moves.

 

I'd say in these precarious times not taking responsibility and hoping for a saviour to come and sort out your problems isn't the wisest of moves.

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1 minute ago, Lamp Of Truth said:

 

I'd say in these precarious times not taking responsibility and hoping for a saviour to come and sort out your problems isn't the wisest of moves.

 

Each to his own, but I know who's side I'd rather be on!

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3 hours ago, B14 said:

Just got another lifetime ban on r/coronavirus again under a different account name...I knew it would happen... but at least I went a few rounds with pro-vaxxers and I mean to tell you...it's frankly terrifying the way their minds think. They will have NO PROBLEM outing those from society who don't take the jabs. How can they not see the terrifying similarities between the current situation and say nazi Germany, Stalinistic Russia, etc.,? History is, indeed, repeating itself.

 

Probably think that they're too clever to taken in by state propaganda the way those in Nazi Germany were.

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2 minutes ago, alexa said:

 

Your not causing me any offence, only God, which in these precarious times that we find ourselves living in, isn't the wisest of moves.

 

I think if there is a divine being....he is in us and among us and inside us...n we all are playing role.........if we were designed in his image........then we all have the power............

 

my wife in the school playground today went toe to toe with teachers, because we wont allow our daughter to use anti-bac gel....so theyve been making our little girl wash her hands 12 times a day.........12 times......her hands were sore, so my wife has demanded a meeting yesterday, without telling me, coz she knows what im like, and gone at these teachers (in the playground because no meetings indoors) so alot of parents watched on as my wife explained about our microbiome, the bodies natural immunity,the stupidy and cowardice of these teachers, and parents.......mouths wide open.......the teachers actually said we agree but wev got no choice.........to my wife screaming wev all got a choice...each and every1 of us have a choice!!! the teachers agreed to not make my daughter over wash her hands................except after the toilet, n b4 dinner.......but scarlett said...all the children in her class did the same...................

 

now my wife is not the type to do this.........

 

this could be a divine moment

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3 minutes ago, Lamp Of Truth said:

 

Probably think that they're too clever to taken in by state propaganda the way those in Nazi Germany were.

Agree, most war era footage is in black and white and it can mean it's easy to detach from that period of history.

if it was in full colour it would be more viceral and real to them. The proles really do need to be shocked and horrified to wake up. 

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