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kj35

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Posts posted by kj35

  1. Copied in case articles disappear.

     

     

    MEDICAL & BIOTECH

    Invisible Ink Could Reveal whether Kids Have Been Vaccinated

    The technology embeds immunization records into a child’s skin

    By Karen Weintraub on December 18, 2019

    M.I.T. engineers have developed a way to store medical information under the skin, using a quantum dot dye that is delivered, along with a vaccine, by a microneedle patch. The dye, which is invisible to the naked eye, can be read later using a specially adapted smartphone. Credit: Second Bay Studios

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    Keeping track of vaccinations remains a major challenge in the developing world, and even in many developed countries, paperwork gets lost, and parents forget whether their child is up to date. Now a group of Massachusetts Institute of Technology researchers has developed a novel way to address this problem: embedding the record directly into the skin.

    Along with the vaccine, a child would be injected with a bit of dye that is invisible to the naked eye but easily seen with a special cell-phone filter, combined with an app that shines near-infrared light onto the skin. The dye would be expected to last up to five years, according to tests on pig and rat skin and human skin in a dish.

    The system—which has not yet been tested in children—would provide quick and easy access to vaccination history, avoid the risk of clerical errors, and add little to the cost or risk of the procedure, according to the study, published Wednesday in Science Translational Medicine.

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    “Especially in developing countries where medical records may not be as complete or as accessible, there can be value in having medical information directly associated with a person,” says Mark Prausnitz, a bioengineering professor at the Georgia Institute of Technology, who was not involved in the new study. Such a system of recording medical information must be extremely discreet and acceptable to the person whose health information is being recorded and his or her family, he says. “This, I think, is a pretty interesting way to accomplish those goals.”

    The research, conducted by M.I.T. bioengineers Robert Langer and Ana Jaklenec and their colleagues, uses a patch of tiny needles called microneedles to provide an effective vaccination without a teeth-clenching jab. Microneedles are embedded in a Band-Aid-like device that is placed on the skin; a skilled nurse or technician is not required. Vaccines delivered with microneedles also may not need to be refrigerated, reducing both the cost and difficulty of delivery, Langer and Jaklenec say.

    Delivering the dye required the researchers to find something that was safe and would last long enough to be useful. “That’s really the biggest challenge that we overcame in the project,” Jaklenec says, adding that the team tested a number of off-the-shelf dyes that could be used in the body but could not find any that endured when exposed to sunlight. The team ended up using a technology called quantum dots, tiny semiconducting crystals that reflect light and were originally developed to label cells during research. The dye has been shown to be safe in humans.

    A close-up microscope image of the microneedle array, which could deliver quantum dots into skin. Credit: K.J. McHugh et al. Science Translational Medicine (2019)

    The approach raises some privacy concerns, says Prausnitz, who helped invent microneedle technology and directs Georgia Tech’s Center for Drug Design, Development and Delivery. “There may be other concerns that patients have about being ‘tattooed,’ carrying around personal medical information on their bodies or other aspects of this unfamiliar approach to storing medical records,” he says. “Different people and different cultures will probably feel differently about having an invisible medical tattoo.”

    When people were still getting vaccinated for smallpox, which has since been eradicated worldwide, they got a visible scar on their arm from the shot that made it easy to identify who had been vaccinated and who had not, Jaklenec says. “But obviously, we didn’t want to give people a scar,” she says, noting that her team was looking for an identifier that would be invisible to the naked eye. The researchers also wanted to avoid technologies that would raise even more privacy concerns, such as iris scans and databases with names and identifiable data, she says.

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    The quantum dots after being administered in the skin of rodents. Credit: K.J. McHugh et al. Science Translational Medicine (2019)

    The work was funded by the Bill & Melinda Gates Foundation and came about because of a direct request from Microsoft founder and philanthropist Bill Gates himself, who has been supporting efforts to wipe out diseases such as polio and measles across the world, Jaklenec says. “If we don’t have good data, it’s really difficult to eradicate disease,” she says.

    The researchers hope to add more detailed information to the dots, such as the date of vaccination. Along with them, the team eventually wants to inject sensors that could also potentially be used to track aspects of health such as insulin levels in diabetics, Jaklenec says.

    This approach is likely to be one of many trying to solve the problem of storing individuals’ medical information, says Ruchit Nagar, a fourth-year student at Harvard Medical School, who also was not involved in the new study. He runs a company, called Khushi Baby, that is also trying to create a system for tracking such information, including vaccination history, in the developing world.

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    Working in the northern Indian state of Rajasthan, Nagar and his team have devised a necklace, resembling one worn locally, which compresses, encrypts and password protects medical information. The necklace uses the same technology as radio-frequency identification (RFID) chips—such as those employed in retail clothing or athletes’ race bibs—and provides health care workers access to a mother’s pregnancy history, her child’s growth chart and vaccination history, and suggestions on what vaccinations and other treatments may be needed, he says. But Nagar acknowledges the possible concerns all such technology poses. “Messaging and cultural appropriateness need to be considered,” he says.

    Rights & Permissions

    ABOUT THE AUTHOR(S)

    Karen Weintraub

    Karen Weintraub is a freelance health and science journalist who writes regularly for the New York Times, STAT and USA Today, among others.

    Credit: Nick Higgins

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  2. On 1/7/2021 at 5:22 PM, rideforever said:

    3,000 ish are supposed to be in ICU for Covid .. which is not much for the biggest employer in Europe, the NHS, with more than a million staff ... and let's not forget the Army who created 8 field hospitals in a few weeks.

     

    BUT   because the NHS does not want to waste capacity what they do is FLEX the size of the ICU every winter depending on demand .. therefore the ICU is always 95% full.

     

    But the ICU changes size according to forecasts ... they add more beds and doctors.  And if demand is light then they close down beds and re-assign doctors.

     

    So the ICU is always at 95% capacity.

     

    Okay ...   so basically people are just fucking stupid, what can you do.

     

    And don't worry about your sheep family ... they are not evil .. .they are just sheep ... and sheep have a job to do ... they are freaked out like everyone else and defend themselves in a sheeplike fashion.  Hopefully it'll all calm down.

     

    It's the newspapers that have created civil war ... and make everyone feel that the world is crazy.  It's not, people are okay.

    But the journalists are alcoholics, and the papers are going out of business so they have poured gasoline on the whole thing.

     

    Absolutely spot on. 

  3. Bill Gates about to publish a book of his solutions for climate change yet calls his private jet his guilty pleasure and is bidding to buy .UK private jet firm. Not only more, one rule for them and another for you, but evidence is mounting that the agenda plan is to cut out all flights for Joe public leaving only the super wealthy able to travel.

     

    The Guardian 

    Bill Gates joins Blackstone in bid to buy British private jet firm

    Gates’ Cascade Investment fund teams up with US private equity firm on offer for Signature Aviation

    Rupert Neate Wealth correspondent

    @RupertNeate

    Sat 9 Jan 2021 08.00 GMT

    40

    Bill Gates has joined a £3bn bidding war to buy the world’s largest private jet operator just as he prepares to publish his new book How to Avoid a Climate Disaster.

    Cascade Investment, the fund that manages much of Gates’s $134bn personal fortune, announced on Friday it had teamed up with US private equity firm Blackstone in a bid for British private jet operator Signature Aviation.

    The Cascade and Blackstone offer came just hours after rival American private equity firm Carlyle made an approach to buy Signature, which handles more than 1.6m private jet flights a year. Cascade is already the biggest investor in Signature with a 19% stake.

    According to a study by academics at Lund University, Gates is one of the world’s biggest “super-emitters” due to his regular private jet travel. He took 59 flights in one year travelling more than 200,000 miles, according to the report, which estimated that Gates’ private jet travel emitted about 1,600 tonnes of carbon dioxide. That compares with a global average of less than five tonnes per person. Researchers have found that private jets emit up to 40 times as much carbon dioxide per passenger than commercial jets.

    Gates, who says in the foreword to his forthcoming book that he has spent a decade investigating the causes and effects of climate change, did not respond to requests for comment about his views on the carbon footprint of private jets.

    The billionaire has previously said that owning private planes was his “guilty pleasure”. In a Reddit Ask Me Anything in 2014, Gates said: “Owning a plane is a guilty pleasure. Warren Buffett called his the Indefensible. I do get to a lot of places for Foundation work I wouldn’t be able to go to without it.”

     

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    © 2021 Guardian News & Media Limited or its affiliated companies. All rights reserved. (modern)

     

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    Earth's Moon

    Sept. 2, 2020

    The Moon Is Rusting, and Researchers Want to Know Why

    The Moon as viewed by NASA's Mariner 10 in 1973, well before research would find signs of rust on the airless surface.

    Credits: NASA/JPL/Northwestern University

    Full image and caption

    While our Moon is airless, research indicates the presence of hematite, a form of rust that normally requires oxygen and water. That has scientists puzzled.

    Mars has long been known for its rust. Iron on its surface, combined with water and oxygen from the ancient past, give the Red Planet its hue. But scientists were recently surprised to find evidence that our airless Moon has rust on it as well.

    A new paper in Science Advances reviews data from the Indian Space Research Organization's Chandrayaan-1 orbiter, which discovered water ice and mapped out a variety of minerals while surveying the Moon's surface in 2008. Lead author Shuai Li of the University of Hawaii has studied that water extensively in data from Chandrayaan-1's Moon Mineralogy Mapper instrument, or M3, which was built by NASA's Jet Propulsion Laboratory in Southern California. Water interacts with rock to produce a diversity of minerals, and M3 detected spectra – or light reflected off surfaces – that revealed the Moon's poles had a very different composition than the rest of it.

    The blue areas in this composite image from the Moon Mineralogy Mapper (M3) aboard the Indian Space Research Organization's Chandrayaan-1 orbiter show water concentrated at the Moon's poles. Homing in on the spectra of rocks there, researcher found signs of hematite, a form of rust.

    Credits: ISRO/NASA/JPL-Caltech/Brown University/USGS

    Full image and caption

    Intrigued, Li homed in on these polar spectra. While the Moon's surface is littered with iron-rich rocks, he nevertheless was surprised to find a close match with the spectral signature of hematite. The mineral is a form of iron oxide, or rust, produced when iron is exposed to oxygen and water. But the Moon isn't supposed to have oxygen or liquid water, so how can it be rusting?

    Metal Mystery

    The mystery starts with the solar wind, a stream of charged particles that flows out from the Sun, bombarding Earth and the Moon with hydrogen. Hydrogen makes it harder for hematite to form. It's what is known as a reducer, meaning it adds electrons to the materials it interacts with. That's the opposite of what is needed to make hematite: For iron to rust, it requires an oxidizer, which removes electrons. And while the Earth has a magnetic field shielding it from this hydrogen, the Moon does not.

    "It's very puzzling," Li said. "The Moon is a terrible environment for hematite to form in." So he turned to JPL scientists Abigail Fraeman and Vivian Sun to help poke at M3's data and confirm his discovery of hematite.

    "At first, I totally didn't believe it. It shouldn't exist based on the conditions present on the Moon," Fraeman said. "But since we discovered water on the Moon, people have been speculating that there could be a greater variety of minerals than we realize if that water had reacted with rocks."

    After taking a close look, Fraeman and Sun became convinced M3's data does indeed indicate the presence of hematite at the lunar poles. "In the end, the spectra were convincingly hematite-bearing, and there needed to be an explanation for why it's on the Moon," Sun said.

    Three Key Ingredients

    Their paper offers a three-pronged model to explain how rust might form in such an environment. For starters, while the Moon lacks an atmosphere, it is in fact home to trace amounts of oxygen. The source of that oxygen: our planet. Earth's magnetic field trails behind the planet like a windsock. In 2007, Japan's Kaguya orbiter discovered that oxygen from Earth's upper atmosphere can hitch a ride on this trailing magnetotail, as it's officially known, traveling the 239,000 miles (385,00 kilometers) to the Moon.

    That discovery fits with data from M3, which found more hematite on the Moon's Earth-facing near side than on its far side. "This suggested that Earth's oxygen could be driving the formation of hematite," Li said. The Moon has been inching away from Earth for billions of years, so it's also possible that more oxygen hopped across this rift when the two were closer in the ancient past.

    Then there's the matter of all that hydrogen being delivered by the solar wind. As a reducer, hydrogen should prevent oxidation from occurring. But Earth's magnetotail has a mediating effect. Besides ferrying oxygen to the Moon from our home planet, it also blocks over 99% of the solar wind during certain periods of the Moon's orbit (specifically, whenever it's in the full Moon phase). That opens occasional windows during the lunar cycle when rust can form.

    The third piece of the puzzle is water. While most of the Moon is bone dry, water ice can be found in shadowed lunar craters on the Moon's far side. But the hematite was detected far from that ice. The paper instead focuses on water molecules found in the lunar surface. Li proposes that fast-moving dust particles that regularly pelt the Moon could release these surface-borne water molecules, mixing them with iron in the lunar soil. Heat from these impacts could increase the oxidation rate; the dust particles themselves may also be carrying water molecules, implanting them into the surface so that they mix with iron. During just the right moments – namely, when the Moon is shielded from the solar wind and oxygen is present – a rust-inducing chemical reaction could occur.

    More data is needed to determine exactly how the water is interacting with rock. That data could also help explain another mystery: why smaller quantities of hematite are also forming on the far side of the Moon, where the Earth's oxygen shouldn't be able to reach it.

    More Science to Come

    Fraeman said this model may also explain hematite found on other airless bodies like asteroids. "It could be that little bits of water and the impact of dust particles are allowing iron in these bodies to rust," she said.

    Li noted that it's an exciting time for lunar science. Almost 50 years since the last Apollo landing, the Moon is a major destination again. NASA plans to send dozens of new instruments and technology experiments to study the Moon beginning next year, followed by human missions beginning in 2024 all as part of the Artemis program.

    JPL is also building a new version of M3 for an orbiter called Lunar Trailblazer. One of its instruments, the High-resolution Volatiles and Minerals Moon Mapper (HVM3), will be mapping water ice in permanently shadowed craters on the Moon, and may be able to reveal new details about hematite as well.

    "I think these results indicate that there are more complex chemical processes happening in our solar system than have been previously recognized," Sun said. "We can understand them better by sending future missions to the Moon to test these hypotheses."

    Andrew Good
    Jet Propulsion Laboratory, Pasadena, Calif.
    818-393-2433
    [email protected]

    Alana Johnson / Grey Hautaluoma
    NASA Headquarters, Washington
    202-672-4780 / 202-358-0668
    [email protected] / [email protected]

    2020-171

    Last Updated: Sept. 4, 2020

    Editor: Tony Greicius

    Tags:  Earth's Moon, Solar System

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    • Like 2
  5. Why on earth have they bought 350 million doses of the vaccine for at best 140 million vaccinations 🤔????? 70 million people x 2 does not 350 million vaccines make. It's scrolling along under that tony Blair piers Morgan interview uncommented on.

    • Like 1
  6. 1 hour ago, Bombadil said:

    Just showed my misses this article. She can remember having a similar type vaccination in Italy as a child. She thinks she was probably six or seven years old. So about 33 years ago. 
    said a pen looking injector with multiple points pressed onto body then covered with wired type plaster. Not remotely like standard. Left a circular imprint/mark on body to show vaccination had been done.

    I think that was probably the Tuberculosis antibody test

    • Like 1
  7. 12 hours ago, Bombadil said:

    I was thinking about this for a while now. Originally they said there would be a three week gap between first and second vaccinations. All of a sudden it was said now twelve weeks was necessary and would not affect the overall vaccination process of an individual. 
    Now if there is something nefarious that will be activated by the second vaccine. I have no doubt somethings in it. A three week gap would potentially mean visible effects appearing before enough have been vaccinated at least once. Obviously in twelve weeks a massively larger proportion of people would be on their way, so to speak. This would mean more are irreversibly compromised by the second vaccination. This benefits the agenda in every way. Once you’ve had it there’s no going back.

    Would not be surprised if they suggest an even longer period between both vaccinations.

    Mother in law's just had her second jab today. I'll let you know what happens, if anything.

     

    • Like 1
  8. On 12/27/2020 at 7:29 PM, JohnB said:

    In reference to Basket Case's post, for Bill Gates to go to jail it would still have to be shown beyond reasonable doubt that he knowingly or recklessly killed, maimed and crippled thousands of Indian and African children. But if we're talking about balance of probabilities in a civil case it's a different matter.

    Wonder where that stands with the corporate homicide and manslaughter laws. Genuine pondering question 

  9. 9 hours ago, peter said:

    I just got hold of the book Ingo Swan recommended by Fred Steckling ( we discovered Alien bases on the moon),I managed to pick it up for half  what people were asking , still expensive though so I hope it's worth it

    I think so. I really rate Ingo. One of the few who actually tried to teach others and not 'Lord it over ' them 

  10. 1 hour ago, Noctua said:

    The problem with all their superlatives (Tier 5, super mutant strain, long-covid) in the media is that people eventually become immune to it.  There is only so much fear a human psyche can take before it starts to shut down and compartmentalize.

     

    This sensationalist reporting is getting further and further into the downright bizarre.  When a newspaper resorts to having to put part of it's headline in capitals to accentuate importance, you know it's struggling for news.

     

    A real pandemic would result in muted headlines this far down the line.  We'd be so petrified of the mounting body count that they'd be no need for sensationalism.  Quite the opposite, in fact.  The government, media and health professionals would be attempting to keep up our spirits and find optimism in the face of adversity.

    No more likes but 👏👏👏👏👏

    • Like 1
  11. As many of us here know this has just been the test run before what Bill Gates calls 'pandemic 2' starts. For the first time I'm now seeing pandemic 2 flagged in the MSM.

     

    Guardian today.

     

    The Guardian

    Coronavirus

    WHO warns Covid-19 pandemic is 'not necessarily the big one'

    Experts tell end of year media briefing that virus is likely to become endemic 

    @MelissaLDavey

    Tue 29 Dec 2020 06.19 GMT

    402

    World Health Organization experts have warned that even though the coronavirus pandemic has been very severe, it is “not necessarily the big one”, and that the world will have to learn to live with Covid-19.

    The “destiny” of the virus is to become endemic, even as vaccines begin to be rolled out in the US and UK, says Professor David Heymann, the chair of the WHO’s strategic and technical advisory group for infectious hazards.

    “The world has hoped for herd immunity, that somehow transmission would be decreased if enough persons were immune,” he told the WHO’s final media briefing for 2020.

    Australia insists WHO inquiry into Covid origin must be robust, despite China tensions

    Read more

    But Heymann, who is also an epidemiologist with the London School of Hygiene and Tropical Medicine, said the concept of herd immunity was misunderstood.

    “It appears the destiny of SARS-CoV-2 [Covid-19] is to become endemic, as have four other human coronaviruses, and that it will continue to mutate as it reproduces in human cells, especially in areas of more intense admission.

    “Fortunately, we have tools to save lives, and these in combination with good public health will permit us to learn to live with Covid-19.”

    The head of the WHO emergencies program, Dr Mark Ryan, said: “The likely scenario is the virus will become another endemic virus that will remain somewhat of a threat, but a very low-level threat in the context of an effective global vaccination program.

    “It remains to be seen how well the vaccines are taken up, how close we get to a coverage level that might allow us the opportunity to go for elimination,” he said. “The existence of a vaccine, even at high efficacy, is no guarantee of eliminating or eradicating an infectious disease. That is a very high bar for us to be able to get over.”

    That was why the first goal of the vaccine was to save lives and protect the vulnerable, Ryan said. “And then we will deal with the moonshot of potentially being able to eliminate or eradicate this virus.”

    Ryan warned that the next pandemic may be more severe. “This pandemic has been very severe … it has affected every corner of this planet. But this is not necessarily the big one,” he said.

    “This is a wake-up call. We are learning, now, how to do things better: science, logistics, training and governance, how to communicate better. But the planet is fragile.

    “We live in an increasingly complex global society. These threats will continue. If there is one thing we need to take from this pandemic, with all of the tragedy and loss, is we need to get our act together. We need to honour those we’ve lost by getting better at what we do every day.”

    WHO chief scientist Dr Soumya Swaminathan told the briefing that being vaccinated against the virus did not mean public health measures such as social distancing would be able to be stopped in future.

    The first role of the vaccine would be to prevent symptomatic disease, severe disease and deaths, she said. But whether the vaccines would also reduce the number of infections or prevent people from passing on the virus remains to be seen.

    Scheme to get Covid vaccine to poorer countries at 'high risk' of failure

    Read more

    “I don’t believe we have the evidence on any of the vaccines to be confident that it’s going to prevent people from actually getting the infection and therefore being able to pass it on,” Swaminathan said. “So I think we need to assume that people who have been vaccinated also need to take the same precautions.”

    The WHO director general, Tedros Adhanom Ghebreyesus, said the end of the year was a time to reflect on the toll the pandemic had taken, but also the progress made. He said the year ahead would see new setbacks and new challenges.

    “For example, new variants of Covid-19, and helping people who are tired of the pandemic continue to combat it,” he said.

    “New ground has been broken, not least with the extraordinary cooperation between the private and public sector in this pandemic. And in recent weeks, safe and effective vaccine rollout has started in a number countries, which is an incredible scientific achievement.

    “This is fantastic, but WHO will not rest until those in need everywhere have access to the new vaccines and are protected.”

     

     

    • Like 1
  12. 3 hours ago, Nemuri Kyoshiro said:

    I honestly don't know. I was told it's taking an age to get a new passport processed and that the passport office is discouraging applications 'because of Covid'.

    I've found the best response in almost all situations is completely ignore the hype and carry on as I would have previously.  Just apply. It'll come.

  13. 1 hour ago, Nemuri Kyoshiro said:

    My sister lives in Menorca. She tells me that life is going on pretty much as normal there. It's a lovely place to go but I'll have to get my passport renewed. I'm told that it is not an easy thing to do these days.

    I don't think there's any difference to passports? What's changed?

  14. 3 hours ago, Martin1234 said:

    What's the likelihood of going on holiday next year? UK or abroad?

     

    I know people don't know for sure but thoughts?

    I've been this year. Three times to Spain. A lot of the restrictions were fear based not legal.  I intend to go back probably March time if not sooner. You might be better looking at an airbnb, rather than a hotel

  15. 11 hours ago, rideforever said:

     

    This is hard evidence for the shrinking of brains for species that become demesticated.

    This is what has happened to human beings for thousands of years, and in the future this will accelerate.  Humans will have smaller and smaller brains.  They are becoming much more sheeplike.  The onslaught of huge expanding populations becomes a deafening herd of sheep that it is harder to escape from.  There are sheep everywhere, there is little space to be yourself or privacy.

    Any shoots of real life are instantly mown down by the sheeple.

    It is happening already hence the movie Idiocracy - the only problem with that movie is that it is the leftwing rather than the right that is most sheeplelike.

    But ... as the world becomes more controlled the brain size will decrease, already there is no need for genitals or gender or the family or the recognition of their race history or people.

    This will continue.

    Thanks ride

    • Like 1
  16. I do like the idea of this . At several points during my working life I did employ this tactic. Specifically once when my line manager decided I was 'fair game ' and sexually harassed me then imposed work restriction after restriction and tried to dick over a promotion, tried to make me lie so he'd have something on me  etc as I wouldn't play ball (!). I could have put a harassment claim in and under that regime ruined my career or do what I did moved to another branch on a sideways move (the boss had scuppered the promotion telling lies about my work). I moved sideways ended up being promoted far far higher than I ever thought I would be and watched as this bloke got the sack 18 months later after doing the same to my friend and another woman. The difference now was everyone was wise to what he'd tried with me, my integrity proved my story, and no one believed him anymore  I am a great believer in if you cannot win the fight move yourself away from the firing line and wait until you can make sure you can actually win.

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